| Catalog Code: | NB300-585 |
| Product Type: | Primary Antibody |
| Product Name: | ATR Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 545 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-ATR |
| Cross Reactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Species Summary: | Hu |
| Background: | Ataxia Telangiectasia Mutated (ATM) and Rad3-related protein (ATR) is a phosphatidylinositol kinase (PK)-related kinase which functions in response to DNA damage and repair as well as at DNA replication checkpoints during the cell cycle. ATR is a member o |
| Alternate Names: | anti-Ataxia Telangiecasia and Rad3 Related antibody, anti-FRAP Related Protein 1 antibody, anti-FRP 1 antibody, anti-Human JTV 1 antibody, anti-protein kinase ATR antibody, anti-Rad3 related protein antibody, anti-SCKL antibody, anti-SCKL1 antibody, anti- |
| Immunogen: | Fusion protein, corresponding to amino acids 400-460 of Human ATR. |
| Localization: | Type I membrane protein (Probable). |
| Purity: | Immunogen affinity purified |
| Buffer: | PBS containing 0.05% sodium azide |
| Packaging: | 0.1 ml purified antisera. |
| Package Size: | 0.1 ml |
| Uses: | This antibody can be used in Western Blot, Immunoprecipitation, and Immunofluorescence. By Western blot, this antibody detects an ~305 kDa protein representing ATR in lysate from UV irradiated K562 cells. Recommended Starting Dilutions*: WB: 1/1000 Not |
| Application Summary: | IF, IP, WB |
| General References: | Schmidt DR & Schreiber SL Molecular association between ATR and two components of the nucleosome remodeling and deacetylating complex, HDAC2 and CHD4. Biochemistry 38:14711-7 (1999). Kim ST et al. Substrate specificities and identificatio |