| Catalog Code: | NB300-504 |
| Product Type: | Primary Antibody |
| Product Name: | NFAT1 Antibody |
| List Price: | 295 |
| Clonality: | Monoclonal |
| Gene ID: | 4773 |
| Host: | Mouse |
| Clone: | 25A10.D6.D2 |
| Isotype: | IgG1 |
| Product Description: | Mouse Monoclonal anti-NFAT1 (25A10.D6.D2) |
| Cross Reactivity: | Reacts with Human, rat, and mouse. Not yet tested in other species. |
| Species Summary: | Hu, Mu, Rt |
| Background: | The nuclear factor of activated T-cells (NFAT) transcription complex is required for the expression of a group of proteins that collectively regulate the immune response. Four NFAT proteins, encoded on separate genes and expressed as several splice varian |
| Alternate Names: | Anti-NFATc antibody, anti-NFATc1 antibody, anti-NFATc2 antibody, anti-NFATc3 antibody, anti-NFATp antibody, anti-NFATx antibody |
| Immunogen: | A synthetic peptide with sequence AISSPSGLAYPDDVLDYGL representing amino acid residues 51-69 of mouse NFAT1-A, B and C isoforms. |
| Specificity: | Detects nuclear factor of activated T-cells (NFAT). This antibody does not cross react with NFAT2 (NFATc, NFATc1). |
| Purity: | IgG purified |
| Buffer: | PBS |
| Packaging: | 0.1 mg IgG purified Mouse ascites. |
| Package Size: | 0.1 mg |
| Uses: | This antibody can be used in Gel shift assay, Immunocytochemistry, Immunoprecipitation, and Western Blot. By Western blot, this antibody detects an ~140 kDa protein representing phosphorylated NFAT1 in resting immune cells, and an ~120 kDa protein in sti |
| Application Summary: | IP, WB, ICC, GS |
| Product References: | 1. Kornau HC et al. Domain interaction between NMDA receptor subunits and the postsynaptic density protein PSD-95. Science 269: 1737-40 (1995). PUBMED:7569905 |
| Novus References: | 1. Bonnet, Sebastien, et al. The nuclear factor of activated T cells in pulmonary arterial hypertension can be therapeutically targeted. Bio. Sci. 104(27): 11418-11423 (2007). |
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