| CatalogCode: | NB300-357 |
| ProductName: | COL4A3BP Antibody |
| Product Description: | Chicken Polyclonal anti-COL4A3BP (C-178) |
| Clone: | C-178 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide: VVEEGEMKVY RREVEENGIV LDPLKATHAV KGVTGHEVCN YFWNVDVRND WETTIENFHV VETLADNAII IYQTHKRVWP ASQRDVLYLS VIRKIPALTE NDPETWIVCN FSVDHDSAPL NNRCVRAKIN VAMICQTLVS PPEGNQEISR DNILCKITYV ANVNPGGWAP ASVLRAVA , corresponding to C terminal amino acids 421-598 of Human COL4A3BP. |
| CrossReactivity: | Cross-reacts with Human, Mouse and Rat. Not yet tested in other species. |
| Packaging: | 0.05 mg Immunogen affinity purified Chicken antisera. |
| Uses: | WB: Predicted molecular weight: 72 kDa. Optimal dilutions/concentrations should be determined by the end user. |
| Background: | COL4A3BP is a kinase that specifically phosphorylates the N terminal region of the non collagenous domain of the alpha 3 chain of type IV collagen, known as the Goodpasture antigen. Goodpasture disease is the result of an autoimmune response directed at this antigen. One isoform of this protein is also involved in ceramide intracellular transport. Two transcripts exist for this gene. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgY |
| Host_Name: | Chicken |
| Buffer: | PBS |
| ListPrice: | 295 |
| AppSummary: | WB |
| SpeciesSummary: | Hu, Mu, Rt |
| ALTnames: | anti-GPBP antibody, anti-Collagen type IV binding protein antibody, anti-StARD11 antibody |
| ProteinTarget: | COL4A3BP antibody [C-178] |
| PackageSize: | 0.05 mg |
| GeneralRef: | General / background references:Raya A et al. Characterization of a novel type of serine/threonine kinase that specifically phosphorylates the human goodpasture antigen. J Biol Chem 274:12642-9 (1999). |