| CatalogCode: | | NB300-345 |
| ProductName: | | C1q Antibody |
| Product Description: | | Chicken Polyclonal anti-C1q |
| Clonality: | | Polyclonal |
| Immunogen: | | Full length plasma C1q protein (Human). |
| CrossReactivity: | | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | | 0.05 mg Immunogen affinity purified Chicken antisera. |
| Uses: | | ELISA: Use at a concentration of 1 ug/ml. ICC: Use at an assay dependent dilution. IHC: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 26 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Control: | | Human plasma C1q protein. |
| Background: | | C1q is a sub-component of the first complement component C1, which is formed by the interaction of C1q with the tetramer C1s-C1r-C1r-C1s. C1q is a member of a family of soluble collagen-like proteins and is composed of three basic subunits termed A, B and C (27,550, 25,200, 23,800 Da respectively) which asociate in the proportion 6 A-B subunits (52, 750 Da) and 3 C-C subunits (47,600 Da), to form whole C1q (459,300 Da). C1q binds to IgG and IgM immune complexes, this activates C1r and C1s, which are also bound to C1q and so initiates the classical pathway of complement activation. |
| Storage: | | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | | Immunogen affinity purified |
| Isotype: | | IgY |
| Host_Name: | | Chicken |
| Buffer: | | PBS |
| ListPrice: | | 285 |
| AppSummary: | | ELISA, IHC, WB, ICC |
| SpeciesSummary: | | Hu |
| ALTnames: | | anti-C1QA antibody, anti-Complement C1q subcomponent subunit A antibody, anti-complement component 1 q subcomponent A chain antibody, anti-Complement component 1 q subcomponent alpha polypeptide antibody, anti-complement component C1q A chain antibody |
| ProteinTarget: | | C1q antibody |
| PackageSize: | | 0.05 mg |
| GeneralRef: | | General / background references:Leigh LE et al. C1q-mediated chemotaxis by human neutrophils: involvement of gClqR and G-protein signalling mechanisms. Biochem J 330 ( Pt 1):247-54 (1998). |
| more information: | | company product webpage |