| CatalogCode: | | NB300-213 |
| ProductName: | | MAP2 Antibody |
| Product Description: | | Chicken Polyclonal anti-MAP2 |
| Clonality: | | Polyclonal |
| Immunogen: | | NB 300-213 was raised against all three MAP2 forms, derived from a single gene by alternate transcription, and all share a C-terminal sequence which includes either three or four microtubule binding peptide sequences, which are very similar to those found in the related microtubule binding protein t (tau). MAP2 isoforms are expressed only in neuronal cells and specifically in the perikarya and dendrites of these cells. |
| CrossReactivity: | | This antibody reacts with human, rat, mouse and cow protein. Other species have not been tested. |
| Packaging: | | 0.05 ml Whole Chicken antisera. |
| Uses: | | NB 300-213 can be used in Western blot and immunofluorescence. |
| Background: | | Microtubules are 25nm diameter protein rods found in most kinds of eukarytic cells. They are polymerized from a dimeric subunit made of one a subunit and one b tubulin subunit. Microtubules are associated with a family of proteins called microtubule associated proteins (MAPs), which includes the protein t (tau) and a group of proteins referred to as MAP1, MAP2, MAP3, MAP4 and MAP5. MAP2 is made up of two ~280kDa apparent molecular weight bands referred to as MAP2a and MAP2b. A third lower molecular weight form, usually called MAP2c, corresponds to a pair of protein bands running at ~70kDa on SDS-PAGE gels. Antibodies to MAP2 are excellent markers on neuronal cells, their perikarya and neuronal dendrites. In contrast t (tau) is found predominantly in neuronal axons. Dendrite specific MAP is found specifically in the dendritic branching of neurons. |
| Storage: | | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | | Whole antisera |
| Isotype: | | IgY (does not bind to either Protein A or G.) |
| Host_Name: | | Chicken |
| ListPrice: | | 285 |
| AppSummary: | | IF, WB |
| SpeciesSummary: | | Bv, Hu, Mu, Rt |
| ALTnames: | | anti-DKFZp686I2148 antibody, anti-MAP2A antibody, anti-MAP2B antibody, anti-MAP2C antibody |
| ProteinTarget: | | MAP2 antibody |
| PackageSize: | | 0.05 ml |
| GeneralRef: | | The characterization of this antibody has not been formally published. |
| Gene_Id: | | 4133 |
| Omim_ID: | | NB100-68258 |
| more information: | | company product webpage |
|