| Catalog Code: | NB300-207 |
| Product Type: | Primary Antibody |
| Product Name: | GABA A receptor alpha 1 subunit Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 2554 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-GABA A receptor alpha 1 subunit |
| Cross Reactivity: | This antibody reacts with rat, human and bovine. Other species have not been tested. |
| Species Summary: | Rt, Hu, Bv |
| Background: | GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA |
| Alternate Names: | anti-EJM antibody, anti-Gaba receptor alpha 1 polypeptide antibody, anti-GABA(A) receptor antibody, anti-GABRA 1 antibody, anti-GABRA1 antibody, anti-Gamma aminobutyric acid (GABA) A receptor alpha 1 antibody |
| Immunogen: | Against a fusion protein consisting of MBP and cytoplasmic loop sequence of the GABA-A receptor alpha 1 subunit. |
| Specificity: | NB 300- 207 reacts with the 51 kDa alpha 1 subunit of rat brain GABA-A. There is no known reactivity with other GABA subunits. There is no homology with other GABA subunits. |
| Packaging: | 0.1 ml of affinity purified rabbit antisera [0.15 mg/ml] in 10mM Hepes (pH 7.5), 150 mM NaCl, 100 ug/ml BSA, and 50% glycerol. |
| Package Size: | 0.1 ml |
| Uses: | NB 300-207 may be used for Western analysis Suggested working dilutions: * Western Blot - 1:1,000 Immunohistochemistry - ND Immunoprecipitation - 15 ug ** *The investigator should determine the optimal dilution for a specific application.** 59% of all GAB |
| Application Summary: | WB, IP |
| General References: | 1. Jechlinger, M., et al, Subunit composition and quantitative importance of hetero-oligomeric receptors: GABA A receptors containing alpha6 subunits. J. Neurosci., 18: 2449-2457 (1998). |
| Product References: | 1. Roberts, D. S., Hu, Y., Lund, I. V., Brooks-Kayal, A. R., and Russek, S. J. (2006) Brain-derived Neurotrophic Factor (BDNF)-induced Synthesis of Early Growth Response Factor 3 (Egr3) Controls the Levels of Type A GABA Receptor{alpha}4 Subunits in Hippo |