| Catalog Code: | NB300-179 |
| Product Type: | Primary Antibody |
| Product Name: | GAP43 Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 2596 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-GAP43 [Ser41] |
| Phosphorylated: | Ser41 |
| Cross Reactivity: | NB 300-179 can be used for detection in rat, human and mouse. Other species have not been tested. |
| Species Summary: | Hu, Mu, Rt |
| Background: | GAP-43 is expressed by developing and regenerating neurons, and to a lesser extent, reactive glial cells. It is used widely to specifically label injured neurons and to score neuronal regeneration. |
| Alternate Names: | anti-Growth Associated Protein 43 antibody, anti-Nerve Growth Related Peptide antibody, anti-Neuromodulin antibody, anti-GAP43 antibody, anti-GAP-43 antibody |
| Immunogen: | NB 300-179 was raised against a synthetic phosphopeptide corresponding to amino acid residues surrounding the phosphorylated Ser41 of rat Gap43. |
| Localization: | Growth cone |
| Specificity: | NB 300-179 is specific for Gap43 phosphorylated at Ser41. The specificity is defined based on NB 300-179's specific immunolabeling in Western blots. This labeling is blocked by the phosphopeptide but not the dephosphopeptide. |
| Packaging: | 0.1 ml Rabbit antisera. |
| Package Size: | 0.1 ml |
| Uses: | NB 300-179 can be used in Western blot where a band is seen at ~ 43 kDa, representing Gap43. In some tissues the antibody also recognizes a lower MW band that is also recognized by the PAN Gap43 antibody and, thus, it is likely to be a breakdown product. |
| Application Summary: | WB |