| Catalog Code: | NB300-170 |
| Product Type: | Primary Antibody |
| Product Name: | GABA-B receptor 2 subunit Antibody |
| List Price: | 295 |
| Clonality: | Polyclonal |
| Gene ID: | 9568 |
| Host: | Rabbit |
| Product Description: | Rabbit Polyclonal anti-GABA-B receptor 2 subunit [Ser892] |
| Phosphorylated: | Ser892 |
| Cross Reactivity: | This antibody reacts with rat, human and mouse. Other species have not been tested. |
| Species Summary: | Hu, Mu, Rt |
| Background: | Gamma-aminobutyric acid (GABA) is the primary inhibitory neurotransmitter in the central nervous system. There are two major classes of GABA receptors the GABAA and the GABAB subtype of receptors. GABAB receptors are heterodimeric G protein-coupled recept |
| Immunogen: | Synthetic phosphopeptide corresponding to amino acid residues surrounding the phosphoSer892 of rat GABA BR2 subunit. |
| Specificity: | NB 300-170 is specific for 110 kDa GABA BR2 subunit phosphorylated at Ser892. |
| Buffer: | 10 mM HEPES [pH7.5] with 150 mM NaCl, 50% glycerol and 100ug/ml BSA |
| Packaging: | 0.01 mg Rabbit antisera. |
| Package Size: | 0.01 mg |
| Uses: | Suggested working dilutions: * Western Blot 1: 1,000 Dot Blot 1:1000 Immunohistochemistry 1: 1,000 Immunofluorescence 1: 1,000-2,000 *The investigator should determine the optimal dilution for a specific application. |
| Application Summary: | WB, IHC, IF |
| General References: | 1.Couve A, Thomas P, Calver AR, Hirst WD, Pangalos MN, Walsh FS, Smart TG, Moss SJ (2002) Cyclic AMPdependent protein kinase phosphorylation facilitates GABAB receptor-effector coupling. Nat Neurosci 5:415-424.2. Sakaba T, Neher E (2003) Direct modulation |
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