| CatalogCode: | NB300-148 |
| ProductName: | GABA A receptor alpha 1 Antibody |
| Product Description: | Rabbit Polyclonal anti-GABA A receptor alpha 1 |
| Clonality: | Polyclonal |
| Immunogen: | N-terminal peptide of rat GABA-A receptor alpha 1 subunit |
| Specificity: | Reacts with the 50 kDa alpha 1 subunit. There is no known reactivity with other GABA subunits. |
| CrossReactivity: | This antibody reacts with human and rat. Other species have not been tested. |
| Packaging: | 0.05 ml Whole antisera Rabbit antisera. |
| Uses: | NB 300-148 may be used for western analysis. |
| Localization: | Membrane; multi pass membrane protein. |
| Background: | GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA (A). Some of these drugs include benzodiazepines, anticonvulsants, and anesthetics. GABA (A) Receptors are comprised of subunits and these are further classified into 3 major groups (alpha, beta, and gamma). The subunits determine the pharmacological characteristics. The alpha 1 subunit has a benzodiazepine pharmacology. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Whole antisera |
| Host_Name: | Rabbit |
| Buffer: | n/a |
| ListPrice: | 295 |
| NovusRef: | 1. Herden, C. J., N. E. Pardo, et al. (2008). Differential Effects of Methylmercury on {gamma}-Aminobutyric Acid Type A Receptor Currents in Rat Cerebellar Granule and Cerebral Cortical Neurons in Culture. J Pharmacol Exp Ther. 324: 517-528. |
| AppSummary: | WB |
| SpeciesSummary: | Hu, Rt |
| ALTnames: | Anti-EJM antibody; Anti-Gaba receptor alpha 1 polypeptide antibody; Anti-GABA(A) receptor subunit alpha 1 antibody; Anti-GABRA 1 antibody; Anti-GABRA1 antibody; Anti-Gamma aminobutyric acid (GABA) A receptor alpha 1 antibody; Anti-Gamma aminobutyric acid A receptor alpha 1 antibody; Anti-Gamma aminobutyric acid receptor subunit alpha 1 antibody |
| ProteinTarget: | GABA A receptor alpha 1 |
| PackageSize: | 0.05 ml |
| GeneralRef: | 1. Mehta, AK, et al, Brain Res. Mol. Brain Res. 67: 194-199, 1999. 2. Poulter, M.O., et al, J. of Neurosci., 19(11): 4654-4661, 1999 3. Brandon, N.J., et al, J. of Biol. Chem., 275(49): 38856-38862, 2000 |