| Catalog Code: | NB300-144 |
| Product Type: | Primary Antibody |
| Product Name: | Laminin Antibody |
| List Price: | 275 |
| Clonality: | Polyclonal |
| Gene ID: | 3911 |
| Host: | Rabbit |
| Isotype: | n/a |
| Product Description: | Rabbit Polyclonal anti-Laminin |
| Cross Reactivity: | Human, mouse and rat laminin. Other species have not been tested. |
| Species Summary: | Hu, Mu, Rt |
| Background: | Laminin antibodies are widely used to label blood vessels and basement membranes. |
| Alternate Names: | anti-Laminin 1+2 antibody |
| Immunogen: | Laminin isolated from mouse EHS tumor. |
| Specificity: | This antibody is pan-specific and reacts well with all laminin isoforms tested: laminin-1 (alpha-1, beta-1, and gamma-1) and laminin-2 (alpha-2, beta-1, and gamma-1) . |
| Purity: | IgG purified |
| Buffer: | PBS |
| Packaging: | 0.1 ml of IgG affinity purified rabbit antisera. |
| Package Size: | 0.1 ml |
| Concentration: | 1 mg/ml |
| Uses: | NB 300-144 can be used for Western blotting where it recognizes a band at 200 and 400 kDa, representing laminin. It may also be used for immunohistochemistry (frozen and paraffin tissue) of laminins in all tissues*. It also functionally inhibits laminin |
| Application Summary: | IHC, WB |
| General References: | 1. Zuo, J., et al. J. Neurobiol. 34: 41-54, 19982. Krekoski, C., et al. J. Neurosci. 21: 6206-6213, 2001. |
| Product References: | 1.McDaniel, S. M., Rumer, K. K., Biroc, S. L., Metz, R. P., Singh, M., Porter, W., and Schedin, P. (2006) Remodeling of the Mammary Microenvironment after Lactation Promotes Breast Tumor Cell Metastasis, 168, 608-620. |
| Novus References: | 1. McDaniel, S.M., et al. Remodeling of the mammary microenvironment after lactation promotes breast tumor cell metastasis. Am. J. Pathol. 168:608-620, 2006. |
| Notes Main: | Pan-specific immunostaining of laminins is enhanced by antigen retrieval with pepsin, especially in paraffin treated tissue. |
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