| Catalog Code: | NB200-630 |
| Product Type: | Primary Antibody |
| Product Name: | XAF1 Antibody |
| List Price: | 325 |
| Clonality: | Polyclonal |
| Gene ID: | 54739 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-XAF1 |
| Cross Reactivity: | Cross-reacts with Human and Mouse. Not yet tested in other species. |
| Species Summary: | Hu, Mu |
| Background: | The inhibitors of apoptosis (IAP) proteins prevent cell death both in vitro and in vivo by virtue of inhibition of distinct caspases. The X-linked Inhibitor of Apoptosis, XIAP, is a key member of the IAP family of proteins. The caspase inhibiting activity |
| Immunogen: | Human XAF-1 (CT) peptide. |
| Purity: | Immunogen affinity purified |
| Buffer: | PBS containing 0.02% sodium azide. |
| Packaging: | 100 micrograms |
| Package Size: | 0.1 mg |
| Concentration: | 1 mg/ml |
| Uses: | WB: Use at a concentration of 0.5 - 2 ug/ml. Detects a band of approximately 32 kDa. IHC (P): Use at a concentration of 2ug/ml. Not tested in other applications. Optimal concentrations should be determined by the end user. |
| Application Summary: | WB, IHCP |
| General References: | 1. Liston P, Fong W, Kelly NL, et al. Identification of XAF1 as an antagonist of XIAP anticaspase activity. Nature Cell Biol 2001; 3: 128-133. 2. Deveraux QL, Takahashi R, Salvesan GS, Reed JC. X-linked IAP is a direct inhibitor of cell-death proteases. N |