| CatalogCode: | NB200-611 |
| ProductName: | APC Antibody |
| Product Description: | Rabbit Polyclonal anti-APC |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide derived from the C-terminus of the human APC protein. |
| CrossReactivity: | Cross-reacts with Human, Mouse and Rat.Not yet tested in other species. |
| Packaging: | 0.5 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | IHC-P: 10 min at RT. Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. WB: Predicted molecular weight: 312 kDa.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Cytoplasmic and Nuclear |
| Control: | Normal colon |
| Background: | APC is associated with structural components of intracellular junctions, including conductin, and it competes with E-cadherin for binding to specific internal regions of both - and -catenin. Like APC, APC2 contains SAMP domains, which are required for conductin binding. Both APC and APC2 regulate the formation of active -catenin-Tcf complexes. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | BSA, 10mM PBS. pH 7.4 |
| ListPrice: | 285 |
| AppSummary: | IHC, WB |
| SpeciesSummary: | Hu, Mu, Rt |
| ALTnames: | anti-Adenomatous Polyposis Coli antibody; Anti- APC antibody; Anti-DP2 antibody; Anti-DP2.5 antibody; Anti-DP3 antibody; Anti-FAP antibody; Anti-FPC antibody; Anti-GS antibody; Anti-Protein APC antibody |
| ProteinTarget: | APC |
| PackageSize: | 0.5 ml |