| CatalogCode: | NB200-573 |
| ProductName: | CD21 Antibody |
| Product Description: | Mouse Monoclonal anti-CD21 (21B9) |
| Clone: | 21B9 |
| Clonality: | Monoclonal |
| Immunogen: | Unfortunately, this information is considered to be commercially sensitive |
| Specificity: | This clone 21B9 reacts with CD21 on 8-cells and dendritic cells. The monoclonal antibody 21B9 is a unique antibody which is also useful to recognize cells with low CD21 expression, such as, a subset of T cells, epithelial cells and astrocytes. |
| CrossReactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | 0.05 ml of IgG3 purified ascites. |
| Uses: | FACS: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 115 kDa. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Type I membrane protein |
| Background: | The monoclonal antibody 21B9 reacts with human CD21. CD21 also known as complement receptor 2 (CR2), C3d receptor or EBV receptor is a 140 kD protein. CD21 is a glycosylated type I transmembrane protein consisting on the extracellular face of a series of 15 or 16 CCP domains. CD21 is the receptor for complement components C3d and iC3b as well as the Epstein-Barr virus (EBV) glycoprotein gp350/220. The soluble CD21 (sCD21) was shown to efficiently trigger CD23 signaling pathways in human monocytes. By inducing release of proinflammatory cytokines and up-regulating expression of molecules involved in antigen presentation, sCD21 modulates critical monocyte functions that may be relevant to allergic and inflammatory disorders. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Protein A purified |
| Isotype: | IgG3 |
| Host_Name: | Mouse |
| Buffer: | Preservative: 0.02% Sodium Azide Constituents: 0.1% BSA, PBS |
| ListPrice: | 295 |
| AppSummary: | FACS, WB |
| SpeciesSummary: | Hu |
| ProteinTarget: | CD21 |
| PackageSize: | 0.05 mg |