| Catalog Code: | NB200-552 |
| Product Type: | Primary Antibody |
| Product Name: | DC-SIGN Antibody |
| List Price: | 325 |
| Clonality: | Polyclonal |
| Gene ID: | 30835 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-DC-SIGN |
| Cross Reactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Species Summary: | Hu |
| Background: | Dendritic cells (DCs) that control immune responses were recently found to capture and transport HIV from the mucosal area to remote lymph nodes, where DCs hand over HIV to CD4+ T lymphocytes. DCs also amplify the amount of virus and extend the duration |
| Alternate Names: | anti-CD209 antibody, anti-Dendritic Cell-Specific ICAM-3 antibody, anti-SIGNR1 antibody, anti-SIGN-R1 antibody |
| Immunogen: | Synthetic peptide, corresponding to amino acids 277-293 of Human DC-SIGN (CD209). |
| Localization: | Cell Membrane and Secreted |
| Specificity: | Detects a band at approximately 44kDa. |
| Purity: | Immunogen affinity purified |
| Buffer: | Preservative: 0.02% Sodium Azide Constituents: PBS |
| Packaging: | 100 micrograms |
| Package Size: | 0.1 mg |
| Concentration: | 0.5 mg/ml |
| Uses: | WB: Use at a concentration of 1 - 2 ug/ml. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user. |
| Application Summary: | WB |
| General References: | 1. Geijtenbeek T.B., et al., (2000), |
| Product References: | 1. Louten, J., van Rooijen, N., and Biron, C. A. (2006) Type 1 IFN Deficiency in the Absence of Normal Splenic Architecture during Lymphocytic Choriomeningitis Virus Infection, 177, 3266-3272. |
| Novus References: | 1. Louten, Jennifer, et al. Type 1 IFN Deficiency in the Absence of Normal Splenic Architecture during Lymphocytic Choriomeningitis Virus Infection. J. Immunol., 177: 3266-3272, 2006 |