| Catalog Code: | NB200-167 |
| Product Type: | Primary Antibody |
| Product Name: | LANA2 Antibody |
| List Price: | 275 |
| Clonality: | Monoclonal |
| Gene ID: | 3911 |
| Host: | Mouse |
| Clone: | CM-A807 |
| Isotype: | IgG1 kappa |
| Product Description: | Mouse Monoclonal anti-LANA2 (CM-A807) |
| Cross Reactivity: | This antibody reacts with the viral LANA2 protein and shows no cross-reactivity to cellular proteins. This antibody reacts with human and mouse viral KSHV proteins. No other species have been tested. |
| Species Summary: | Vi, Hu, Mu |
| Background: | LANA2 (latency-associated nuclear antigen) is an inhibitor of p53-induced transcription in reporter assays and may be an apoptosis antagonist. It is a nuclear protein associated with Kaposi's sarcoma-associated herpes virus (KSHV), or human herpes v |
| Alternate Names: | anti-LANA-2 antibody, anti-LANA 2 antibody, anti-Latency-associated nuclear antigen 2 antibody |
| Immunogen: | Recombinant LANA2 fusion protein. |
| Localization: | Nuclear |
| Specificity: | This antibody is specific for KSHV LANA2 (residues 143-310 epitope recognition). |
| Packaging: | 0.1ml Mouse ascites. |
| Package Size: | 0.1ml |
| Concentration: | 2 mg/ml |
| Uses: | This antibody is useful for Western blot, immunofluorescence, and immunoprecipitation. By Western blot, this antibody recognizes a viral protein in KSHV infected B-cells (~66-70 kDa). |
| Application Summary: | IF, IP, WB |
| Product References: | 1. Rivas, C., et al. Kaposi's Sarcoma-Associated Herpesvirus LANA2 is a B-Cell-Specific Latent Viral Protein that Inhibits p53. J. of Virology. 75(1): 429-438, (2001). |