| CatalogCode: | | NB200-126 |
| ProductName: | | BRAF35 Antibody |
| Product Description: | | Rabbit Polyclonal anti-BRAF35 |
| Clonality: | | Polyclonal |
| Immunogen: | | Residues 31-50 [KQERGEGPRA GEKGSHEEEP] of the human structural DNA-binding protein BRAF35. |
| CrossReactivity: | | Human. May react with mouse protein. Other species have not been tested. |
| Packaging: | | 0.1 mg IgG purified Rabbit antisera. |
| Uses: | | This antibody is useful for Western blot. |
| Background: | | Mutations of the human BRCA2 gene confer susceptibility to breast cancer. A structural DNA binding component has been identified and is designated as BRCA2-Associated Factor 35 (BRAF35). There is a close association of the BRAF35/BRCA2 complex with condensed chromatin coincident with histone H3 phosphorylation. Experimental evidence suggests a role for the BRCA2/BRAF35 complex in the modulation of cell cycle progression. |
| Storage: | | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | | IgG purified |
| Isotype: | | IgG |
| Host_Name: | | Rabbit |
| Buffer: | | PBS |
| ListPrice: | | 285 |
| AppSummary: | | WB |
| SpeciesSummary: | | Hu |
| ALTnames: | | anti-BRCA 2 Associated Factor (35kDa) antibody, anti-High Mobility Group Protein 20B antibody, anti-HMG 20B antibody |
| ProteinTarget: | | BRAF35 antibody |
| PackageSize: | | 0.1 mg |
| Homology: | | 80% homology with mouse protein. |
| GeneralRef: | | 1. Marmorstein, L., et al. A human BRCA2 complex containing a structural DNA binding component influences cell cycle progression. Cell. 104: 247-257 (2001). |
| more information: | | company product webpage |