| CatalogCode: | NB120-9384 |
| ProductName: | Cytokeratin 14 Antibody |
| Product Description: | Mouse Monoclonal anti-Cytokeratin 14 (SPK-14) |
| Clone: | SPK-14 |
| Clonality: | Monoclonal |
| Immunogen: | Synthetic peptide: KVVSTHEQVLRTKN (Human) conjugated to KLH. |
| Specificity: | This antibody reacts exclusively with cytokeratin 14. |
| CrossReactivity: | Cross-reacts with Human and Cat.Not yet tested in other species. |
| Packaging: | 1 ml Liquid containing 0.1% sodium azide |
| Localization: | Cytokeratin 14 is present in basal cell compartments of stratified and combined epithelia. |
| Background: | Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 ? 7.8. The individual human cytokeratins are designated 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium.Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Tissue culture supernatant |
| Isotype: | IgG1 kappa |
| Host_Name: | Mouse |
| Buffer: | n/a |
| ListPrice: | 330 |
| AppSummary: | FACS, ICC, IHC-Fr, WB |
| SpeciesSummary: | Hu, Fe |
| ProteinTarget: | Cytokeratin 14 |
| PackageSize: | 1 ml |
| GeneralRef: | General / background references:Bonfrer JM et al. Monoclonal antibody M3 used in tissue polypeptide-specific antigen assay for the quantification of tissue polypeptide antigen recognizes keratin 18. Tumour Biol 15:210-22 (1994). Ivanyi D et al. Patterns of expression of feline cytokeratins in healthy epithelia and mammary carcinoma cells. Am J Vet Res 53:304-14 (1992). |
order or
more information: | company product webpage |
| request information: |
|