| request information: |
|
| Catalog Code: | NB120-8319 |
| Product Name: | IL-1 beta Antibody |
| Product Description: | Mouse Monoclonal anti-IL-1 beta (6E10) |
| Clone: | 6E10 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Concentration: | 2.8 mg/ml |
| Immunogen: | Recombinant beta human Interleukin-1 |
| Specificity: | This antibody reacts with three different and spares determinants on Interleukin-1 beta molecule. It does not inhibit the biological activity of Interleukin-1. |
| Cross Reactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | 0.2 mg protein A purified Mouse ascites. |
| Uses: | For 2 site enzyme immunoassay, we recommend to use a mixture of this antibody and NB120-8320 for coating, in conjunction with NB120-8321 for labeling. For IHC on frozen and parafin embedded sections, use formalin with 2.5% glutaraldehyde as a fixative. |
| Localization: | Secreted |
| Background: | Interleukin 1 (IL1), originally known as lymphocyte activating factor (LAF), activates T cells and lymphocytes, which then proliferate and secrete interleukin 2. IL1 is primarily released from stimulated macrophages and monocytes, but also is released from several other cell types, and is thought to play a key role in inflammatory and immune responses. The two closely related agents, interleukin1 alpha (IL1 alpha) and interleukin1 beta (IL1 beta) bind to the same cell surface receptor, elicit nearly identical biological responses and share 25% homology in their amino acid sequence. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | protein A purified |
| Isotype: | IgG2a |
| Host Name: | Mouse |
| Buffer: | PBS, pH 7.4 |
| Application Summary: | ELISA, immunohistochemistry |
| Species Summary: | Hu, |
| Alternate Names: | anti-Catabolin antibody, anti-H1 antibody, anti-Hematopoietin 1 antibody, anti-IFN beta inducing factor antibody, anti-IL 1B antibody, anti-IL1B antibody, anti-IL1F2 antibody, anti-Interleukin 1 beta precursor antibody, anti-LAF antibody, anti-OAF antibody, anti-Osteoclast activating factor antibody, anti-Preinterleukin beta antibody, anti-Pro interleukin 1 beta antibody |
| Package Size: | 0.2 mg |
| Preservative: | 0.1% sodium azide |
| Notes Main: | This antibody can be used in a sandwich ELISA (coating - conjugate) with the following clone: 6E10 and 11E5 for coating and MAb 5C10 for labeling. For Sandwich ELISA pair this antibody with: NB120-8320 and NB120-8321 |
order or
more information: | company product webpage |