| Catalog Code: | NB120-830 |
| Product Type: | Primary Antibody |
| Product Name: | FGF Receptor 1 Antibody |
| List Price: | 330 |
| Clonality: | Monoclonal |
| Gene ID: | 2260 |
| Host: | Mouse |
| Clone: | M1C4 |
| Isotype: | IgG1 |
| Product Description: | Mouse Monoclonal anti-FGF Receptor 1 (M1C4) |
| Cross Reactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Species Summary: | Hu |
| Immunogen: | Recombinant human ectodomain of FGFr1a expressed in E. coli beginning with pro23; antigen contained NH2-terminal gly-ser-pro-gly-ile and COOH-terminal glu-phe sequences. |
| Epitope: | COOH-terminus of unique NH2-terminal Ig loop of FGFr1. Epitope is within the sequence between glu75 and ser119 of FGFr1a. Epitope is masked in undenatured FGFr1a. |
| Specificity: | Reacts with alpha isoform of FRFR1. |
| Purity: | Protein G purified |
| Buffer: | PBS with 0.02% sodium azide |
| Packaging: | 125 micrograms |
| Package Size: | 0.125 mg |
| Uses: | Western blotting: at 1 ug/ml recognizes 10 ng recombinant bacterial, baculo-viral, or native FGFr1.Immunoprecipitation: Ig loop I fragment of denatured, intact FGFr1a.Immunohistochemistry: untested; predicted to be poor due to masked epitope. |
| Application Summary: | IP, WB |
| General References: | General / background references:Xu J et al. Expression and immunochemical analysis of rat and human fibroblast growth factor receptor (flg) isoforms. J Biol Chem 267:17792-803 (1992). |