| CatalogCode: | NB120-8290 |
| ProductName: | Troponin I Antibody |
| Product Description: | Mouse Monoclonal anti-Troponin I (22B11) |
| Clone: | 22B11 |
| Clonality: | Monoclonal |
| Immunogen: | Unphosphorylated form of cardiac troponin I (amino acid residues 20-24) |
| Epitope: | 20-24 aa |
| Specificity: | This antibody detects the unphosphorylated form of cardiac troponin I.No cross-reaction with mono or biphosphorylated troponin I. |
| CrossReactivity: | Cross-reacts with Human and Pig.Does not cross-react with Mouse, Rat, Cow, Cat, Dog, Fish, Goat or Rabbit.Not yet tested in other species. |
| Packaging: | 0.2 mg |
| Uses: | ELISA: Use at an assay dependent dilution. EIA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Predicted molecular weight: 25 kDa. Can be paired for ELISA with <ab8289>Mouse monoclonal [19C7] to cardiac Troponin I</ab> and <ab10232>Mouse monoclonal [8E10] to cardiac Troponin I</ab>, (see figures). Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Storage: | Store at 4C. Do not freeze. |
| Isotype: | IgG2b |
| Host_Name: | Mouse |
| Buffer: | PBS with pH 7.4 |
| ListPrice: | 295 |
| AppSummary: | EIA, ELISA, WB |
| SpeciesSummary: | Hu |
| ProteinTarget: | Troponin I |
| PackageSize: | 0.2 mg |
| GeneralRef: | General / background references:Sarko J & Pollack CV Cardiac troponins. J Emerg Med 23:57-65 (2002). Gomes AV et al. The role of troponins in muscle contraction. IUBMB Life 54:323-33 (2002). Hamm CW Acute coronary syndromes. The diagnostic role of troponins. Thromb Res 103 Suppl 1:S63-9 (2001). Labugger R et al. Extensive troponin I and T modification detected in serum from patients with acute myocardial infarction. Circulation 102:1221-6 (2000). Wu AH et al. Characterization of cardiac troponin subunit release into serum after acute myocardial infarction and comparison of assays for troponin T and I. American Association for Clinical Chemistry Subcommittee on cTnI Standardization. Clin Chem 44:1198-208 (1998). Katrukha AG et al. Troponin I is released in bloodstream of patients with acute myocardial infarction not in free form but as complex. Clin Chem 43:1379-85 (1997). Cummins B et al. Cardiac-specific troponin-I radioimmunoassay in the diagnosis of acute myocardial infarction. Am Heart J 113:1333-44 (1987). |
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