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| Catalog Code: | NB120-8102 |
| Product Name: | MCP 1 Antibody |
| Product Description: | Mouse Monoclonal anti-MCP 1 (MNA1) |
| Clone: | MNA1 |
| Clonality: | Monoclonal |
| ListPrice: | 475 |
| Immunogen: | Recombinant human MCP-1 |
| Specificity: | The antibody reacts with both human natural and recombinant MCP-1 in ELISA. The antigen specificity was assessed by ELISA. The antigen specificity was further assessed by immunoprecipitation and western blot. No cross-reactivities with other cytokines have been detected. |
| Cross Reactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Packaging: | 0.1 mg Purified Ig in PBS, containing 0.02% sodium azide and 0.1% BSA. |
| Uses: | The antibody is useful for neutralization of human MCP-1 in bio-assays. Furthermore the antibody can be used to stain cells containing MCP-1 in frozen sections as well as in cells cultured on cover slips. MCP-1 can be detected in western blot using the antibody. |
| Localization: | Secreted |
| Background: | This chemotactic factor attracts monocytes and basophils but not neutrophils or eosinophils and augments monocyte anti-tumor activity. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. It may be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | IgG purified |
| Isotype: | IgG1 |
| Host Name: | Mouse |
| Buffer: | PBS with 0.1% BSA pH7.2 |
| Application Summary: | Immunocytochemistry, Immunohistochemistry-Frozen, Western Blot, Functional, |
| Species Summary: | Hu, |
| Alternate Names: | anti-CCL2 antibody, anti-Chemokine C C motif ligand 2 antibody, anti-Chemokine CC Motif Ligand 2 antibody, anti-GDCF 2 antibody, anti-GDCF 2 HC11 antibody, anti-GDCF2 antibody, anti-HC11 antibody, anti-HSMCR30 antibody, anti-MCAF antibody, anti-MCP 1 antibody, anti-MGC9434 antibody, anti-Monocyte chemoattractant protein 1 antibody, anti-Monocyte chemotactic and activating factor antibody, anti-Monocyte chemotactic protein 1 antibody, anti-Monocyte secretory protein JE antibody, anti-SCYA2 antibody, anti-Small inducible cytokine A2 antibody, anti-Small inducible cytokine subfamily A Cys Cys member 2 antibody, anti-SMC CF antibody, anti-SMCCF antibody |
| Package Size: | 0.1 mg |
| Preservative: | 0.02% sodium azide |
| Notes Main: | Monocyte chemotactic protein-1 (MCP-1) is also known as MCAF. |
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