| Catalog Code: | NB120-7978 |
| Product Type: | Primary Antibody |
| Product Name: | Caspase 1 Antibody |
| List Price: | 330 |
| Clonality: | Polyclonal |
| Gene ID: | 834 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-Caspase 1 |
| Cross Reactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Species Summary: | Hu |
| Immunogen: | Synthetic peptide (Human) (N terminal). |
| Localization: | Cytoplasmic |
| Specificity: | Reacts with human caspase-1 precursor (also designated ICE), non cross-reactive with caspase-1 p10 or caspase-1 p20. |
| Purity: | IgG purified |
| Buffer: | PBS with 0.1% sodium azide |
| Packaging: | 1 millilitres Each vial contains 200 ug/ml of affinity purified rabbit IgG, in 1 ml PBS containing 0.1 % sodium azide and 0.2% gelatin. |
| Package Size: | 1 ml |
| Application Summary: | IHC-Fr, IP, WB |
| General References: | General / background references:Slee EA et al. Executioner caspase-3, -6, and -7 perform distinct, non-redundant roles during the demolition phase of apoptosis. J Biol Chem 276:7320-6 (2001). Zhang W et al. Involvement of caspases in 4-hy |
| Notes Main: | Caspases are mammalian proteases that regulate many of the morphological and biochemical features of apoptosis. The currently identified caspases can be divided into three groups: apoptotic initiators, apoptotic executioners, and inflammatory mediators (1 |