| CatalogCode: | NB120-7166 |
| ProductName: | Integrin alpha v beta 3 Antibody |
| Product Description: | Mouse Monoclonal anti-Integrin alpha v beta 3 (BV3) |
| Clone: | BV3 |
| Clonality: | Monoclonal |
| Specificity: | This monoclonal antibody binds to human 3 integrin present on human endothelium cells. |
| CrossReactivity: | Cross-reacts with Human, Rat and Chicken. Not yet tested in other species. |
| Packaging: | 0.05 mg IgG purified Mouse ascites. |
| Uses: | ImmunoassaysImmunoprecipitation Flow cytometry |
| Background: | Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Integrin alpha V beta 3 is the predominant integrin of osteoclasts (bone resorbing cells) and is upregulated in malignant melanoma. Integrin alpha V beta 3 binds to a range of ECM proteins (e.g. vitronectin, fibrinogen, fibronectin) via an Arg-Gly-Asp (RGD) motif. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | IgG purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | PBS with 0.2% BSA |
| ListPrice: | 325 |
| AppSummary: | FACS, IP, IA |
| SpeciesSummary: | Ch, Hu, Rt |
| ALTnames: | anti-CD 51 antibody, anti-CD 61 antibody, anti-CD51 antibody, anti-CD51 antigen antibody, anti-CD61 antibody, anti-CD61 antigen antibody, anti-GP3A antibody, anti-GPIIIa antibody, anti-Integrin alpha V antibody, anti-Integrin beta 3 antibody, anti-Integrin beta chain beta 3 antibody, anti-ITGAV antibody, anti-ITGB 3 antibody, anti-ITGB3 antibody, anti-MSK 8 antibody, anti-MSK8 antibody, anti-Platelet glycoprotein IIIa antibody, anti-Platelet glycoprotein IIIa precursor antibody, anti-Platelet membrane glycoprotein IIIa antibody, anti-Vitronectin receptor alpha polypeptide antibody, anti-vitronectin receptor antibody, anti-Vitronectin receptor subunit alpha antibody, anti-VNRA antibody |
| ProteinTarget: | Integrin alpha v beta 3 |
| PackageSize: | 0.05 mg |
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