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| Catalog Code: | NB120-6085 |
| Product Name: | FXR2 Antibody |
| Product Description: | Mouse Monoclonal anti-FXR2 (A42) |
| Clone: | A42 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Concentration: | 1 mg/ml |
| Immunogen: | His6-FXR2s human fusion protein produced in a bacterial pET system |
| Cross Reactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Packaging: | 0.05 ml purified Mouse IgG |
| Uses: | ELISA: Use at an assay dependent dilution. IF: Use at an assay dependent dilution. IP: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. Detects a band of approximately 92 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Cytoplasmic |
| Background: | FXR2 is a RNA binding protein containing two KH domains and one RCG box, which is similar to FMRP and FXR1. It associates with polyribosomes, predominantly with 60S large ribosomal subunits. It may self-associate or interact with FMRP and FXR1. Fragile X syndrome is caused by the absence of the fragile X mental-retardation protein (FMRP). FMRP is the archetype of a class of cytoplasmic mRNA-binding proteins that includes the fragile X-related 1 and 2 proteins (FXR1 and FXR2). The fragile X-related proteins FXR1 and FXR2 contain a functional nucleolar-targeting signal equivalent to the HIV-1 regulatory proteins. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Isotype: | IgG1 |
| Host Name: | Mouse |
| Buffer: | 0.01 M phosphate buffered saline, pH 7.4, |
| Application Summary: | ELISA, immunofluorescence, immunoprecipitation, Western Blot |
| Species Summary: | Hu, |
| Alternate Names: | anti-FMR1L2 antibody, anti-Fragile X mental retardation 1 like 2 antibody, anti-Fragile X mental retardation gene autosomal homolog 2 antibody, anti-Fragile X mental retardation syndrome related protein 2 antibody, anti-FXR 2 antibody, anti-FXR2 PEN antibody, anti-Human fragile X mental retardation syndrome related protein FXR2 mRNA complete cds antibody |
| Package Size: | 0.05 ml |
| Preservative: | 15 mM sodium azide. |
| General References: | General / background references:Zhang Y et al. The fragile X mental retardation syndrome protein interacts with novel homologs FXR1 and FXR2. EMBO J 14:5358-66 (1995). |
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more information: | company product webpage |