| request information: | |
| Catalog Code: | NB120-5994 |
| Product Name: | TACI Antibody |
| Product Description: | Rabbit Polyclonal anti-TACI |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Concentration: | 0.5 mg/ml |
| Immunogen: | Synthetic peptide (Human). |
| Cross Reactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Packaging: | 0.05 mg Immunogen affinity purified Rabbit antisera. |
| Uses: | In Western Blot predicted molecular weight 32 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Type III membrane protein |
| Background: | TACI is a lymphocyte specific member of the tumor necrosis factor (TNF) receptor superfamily. It interacts with calcium-modulator and cyclophilin ligand (CAML). The protein binds to both APRIL and BAFF and induces activation of the transcription factors NFAT (nuclear-factor of activated T cells), AP1, and NF kappa B and plays a crucial role in humoral immunity by interacting with a TNF ligand. This gene is located within the Smith Magenis syndrome region on chromosome 17. |
| Storage: | 4°C |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | PBS |
| Application Summary: | Western Blot 2 to 5 ìg/ml |
| Species Summary: | Hu, |
| Alternate Names: | anti-CD 267 antibody, anti-CD267 antibody, anti-CD267 antigen antibody, anti-CVID antibody, anti-FLJ39942 antibody, anti-MGC133214 antibody, anti-MGC39952 antibody, anti-TNFRSF 13B antibody, anti-TNFRSF 14B antibody, anti-TNFRSF13B antibody, anti-TNFRSF13B protein antibody, anti-TNFRSF14B antibody, anti-Transmembrane activator and CAML interactor antibody, anti-Tumor necrosis factor receptor 13B antibody, anti-Tumor necrosis factor receptor superfamily member 13B antibody |
| Package Size: | 0.05 mg |
| Preservative: | 0.02% Sodium Azide |
| Notes Main: | Stable for one year. |
| General References: | General / background references:Moore PA et al. BLyS: member of the tumor necrosis factor family and B lymphocyte stimulator. Science 285:260-3 (1999). Schneider P et al. BAFF, a novel ligand of the tumor necrosis factor family, stimulates B cell growth. J Exp Med 189:1747-56 (1999). Shu HB et al. TALL-1 is a novel member of the TNF family that is down-regulated by mitogens. J Leukoc Biol 65:680-3 (1999). |
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