| Catalog Code: | NB120-5791 |
| Product Type: | Primary Antibody |
| Product Name: | Retinoic Acid Receptor alpha Antibody |
| List Price: | 330 |
| Clonality: | Polyclonal |
| Gene ID: | 5914 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-Retinoic Acid Receptor alpha |
| Cross Reactivity: | Cross-reacts with Human and Mouse.Expected to cross-react with Chicken (88% identity with immunogen), Rat (100% identity with immunogen) due to sequence homology.Not yet tested in other species. |
| Species Summary: | Hu, Mu |
| Alternate Names: | anti-Acute Promelocytic Leukemia Breakpoint Cluster Region antibody, anti-RAR alpha form antibody, anti-RARA antibody, anti-RARA/PML Fusion Gene antibody |
| Immunogen: | Synthetic peptide: SPSLSPSSHRSSPATQSP, corresponding to amino acids 444-462 of Mouse Retinoic Acid Receptor alpha. |
| Localization: | Mainly cytoplasmic and weakly nuclear. Upon TNF activation and subsewuent phosphorylation it translocates from the cytoplasm to the nucleus. |
| Specificity: | This antibody does not detect RAR beta or gamma forms. |
| Purity: | Whole antisera |
| Buffer: | Preservative: 0.05% Sodium AzideConstituents: PBS |
| Packaging: | 100 microlitres |
| Package Size: | 0.1 ml |
| Uses: | WB: Use at a dilution of 1/1000. Detects a band of approximately 45 kDa (predicted molecular weight: 55 kDa) representing RAR alpha from SH-SY5Y cell extracts. Can be blocked with <ab4910>Retinoic Acid Receptor alpha peptide</ab>Not tested in |
| Application Summary: | WB |
| General References: | General / background references:Ali M et al. Identification of human, mouse, and rat retinoic acid receptor alpha using monoclonal antibodies. Biochem Biophys Res Commun 182:1032-9 (1992). |