| Catalog Code: | NB120-5781 |
| Product Type: | Primary Antibody |
| Product Name: | GABA A Receptor alpha 1 Antibody |
| List Price: | 330 |
| Clonality: | Polyclonal |
| Gene ID: | 29705 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-GABA A Receptor alpha 1 |
| Cross Reactivity: | Cross-reacts with Rat.Not yet tested in other species. |
| Species Summary: | Rt |
| Background: | GABA (A) receptors are ligand-gated chloride channels that play a role as inhibitory neurotransmitters. They are known targets for certain classes of environmental and pharmaceutical compounds because a number of drugs interact with binding sites on GABA |
| Immunogen: | Fusion protein (Rat) consisting of MBP and cytoplasmic loop sequence of the GABA-A receptor alpha 1 subunit. |
| Specificity: | This antibody reacts with the 51 kDa alpha 1 subunit of rat brain GABA A. There is no known reactivity with other GABA subunits. There is no homology with other GABA subunits. |
| Purity: | Immunogen affinity purified |
| Buffer: | 10 mM Hepes (pH7.5), 150 mM NaCl, 100 ug/ml BSA and 50% glycerol |
| Packaging: | 100 microlitres |
| Package Size: | 0.1 ml |
| Uses: | IP: Use 15 ug (59% of all GABA-A receptors in dodecylsulfate extracts of rat forebrains). WB: Use at a dilution of 1/1000. Detects a band of approximately 51 kDa (predicted molecular weight: 55 kDa). Not tested in other applications.Optimal dilutions/conc |
| General References: | General / background references:Jechlinger M et al. Subunit composition and quantitative importance of hetero-oligomeric receptors: GABAA receptors containing alpha6 subunits. J Neurosci 18:2449-57 (1998). |