| Catalog Code: | NB120-4764 |
| Product Type: | Primary Antibody |
| Product Name: | VAV 3 Antibody |
| List Price: | 330 |
| Clonality: | Polyclonal |
| Gene ID: | 10451 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-VAV 3 [Tyr173] |
| Phosphorylated: | Tyr173 |
| Cross Reactivity: | Cross-reacts with Mouse.Expected to cross-react with Chicken (92% identity with immunogen), Human (100% identity with immunogen) due to sequence homology.Not yet tested in other species. |
| Species Summary: | Mu |
| Background: | Vav proteins belong to the guanidine nucleotide exchange factor family of proteins that couple receptors to Rho-GTPases. The VAV family has currently three members in mammalian cells (VAV 1, VAV 2, and VAV 3). VAV 1 contains multiple protein binding motif |
| Alternate Names: | anti-VAV 3 antibody, anti-VAV 3 oncogene antibody, anti-VAV 3 protein antibody, anti-VAV-3 antibody, anti-VAV-3 oncogene antibody, anti-VAV-3 protein antibody, anti-VAV3 oncogene antibody, anti-VAV3 protein antibody |
| Immunogen: | Synthetic peptide (Human) derived from a region of human VAV 3 that contains tyrosine 173. The sequence is conserved in mouse. |
| Purity: | Immunogen affinity purified |
| Buffer: | Preservative: 0.05% Sodium AzideConstituents: PBS, 1.0mg/ml BSA (IgG, protease free). pH 7.3 |
| Packaging: | 50 microlitres |
| Package Size: | 0.05 ml |
| Uses: | WB: Use at a concentration of 0.1 - 1.0 ug/ml. Predicted molecular weight: 102 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Application Summary: | WB |
| General References: | General / background references:Sachdev P et al. Distinct role of phosphatidylinositol 3-kinase and Rho family GTPases in Vav3-induced cell transformation, cell motility, and morphological changes. J Biol Chem 277:17638-48 (2002). Fujikaw |