| request information: |
|
| Catalog Code: | NB120-3612 |
| Product Name: | Rab11 Antibody |
| Product Description: | Rabbit Polyclonal anti-Rab11 |
| Clonality: | Polyclonal |
| ListPrice: | 285 |
| Immunogen: | Synthetic peptide: M(1)GTRDDEYDYLFKVVLIC(17)Immunizing peptide corresponds to amino acid residues 1-17 from human Rab 11. This sequence is completely conserved in human, mouse and rat and 94% conserved in C. elegans and amphibians. |
| Specificity: | NB120-3612 detects Rab 11 from human and non-human primate samples. |
| Cross Reactivity: | Cross-reacts with Human and Primate. Expected to cross-react with Rat and Mouse due to sequence homology. Not yet tested in other species. |
| Packaging: | 0.2 mg Liquid. |
| Uses: | Western blot: use at a concentration of 6.6ug/ml.Not tested in other applications.Optimal dilutions / concentrations should be determined by the end user.By Western blot, this antibody detects an ~22 kDa protein representing Rab 11 in CV1, PC3, and HeLa cell extract. Another less prominent, unknown band is also detected by this antibody at ~35 kDa. |
| Localization: | Located on the cytoplasmic face of organelles and vesicles. |
| Background: | Rab proteins are low-molecular-weight GTP-binding proteins that form the largest branch of the Ras superfamily of GTPases. Located on the cytoplasmic face of organelles and vesicles, rab proteins are involved in intracellular membrane fusion reactions. Three membrane proteins, synaptosomal associated protein of 25 kDa (SNAP-25), synaptobrevin, and syntaxin, form the core of a ubiquitous membrane fusion machine that interacts with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and a-SNAP. Rab proteins, in coordination with the core fusion machinery and Munc-18, help to mediate vesicle docking and fusion. There exist over 40 Rab proteins that have been described in mammals. Rab 11 is a known marker for protein trafficking, sorting, and recycling in the endosomal pathway. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | PBS |
| Application Summary: | Western Blot 6.6 ug/ml |
| Species Summary: | Hu, Mk, |
| Alternate Names: | anti-GTP binding protein YPT3 antibody, anti-MGC1490 antibody, anti-Rab 11 antibody, anti-RAB 11A antibody, anti-RAB 11A member oncogene family antibody, anti-RAB 11B antibody, anti-RAB11 A antibody, anti-RAB11A antibody, anti-RAB11A member RAS oncogene family antibody, anti-RAB11B antibody, anti-RAB11B member RAS oncogene family antibody, anti-Ras related protein Rab 11A antibody, anti-Ras related protein Rab 11B antibody, anti-YL 8 antibody, anti-YL8 antibody, anti-YPT 3 antibody, anti-YPT3 antibody |
| Package Size: | 0.2 mg |
| Preservative: | 2mg/ml BSA and 0.05% sodium azide |
order or
more information: | company product webpage |
|