| Catalog Code: | NB120-3451 |
| Product Type: | Primary Antibody |
| Product Name: | Munc 18 Antibody |
| List Price: | 330 |
| Clonality: | Polyclonal |
| Gene ID: | 6812 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-Munc 18 |
| Cross Reactivity: | Cross-reacts with Rat.Expected to cross-react with Human, Mouse, Cow and Dog due to sequence homology.Not yet tested in other species. |
| Species Summary: | Rt |
| Background: | Munc-18 is a cytosolic brain protein of ~67 kDa which plays a key role in vesicle membrane fusion events with the plasma membrane. Functional interactions have been demonstrated to exist between Munc-18, synaptosomal associated protein of 25 kDa (SNAP-25) |
| Immunogen: | Synthetic peptide: V(58)EDINKRREPIPS(70).Immunizing peptide corresponds to amino acid residues 58-70 from human Munc 18. This sequence is completely conserved between human, mouse, rat, bovine, and canine Munc 18. |
| Purity: | Immunogen affinity purified |
| Buffer: | PBS, 1 mg/ml BSA and 0.05% sodium azide |
| Packaging: | 100 micrograms Liquid. |
| Package Size: | 0.1 mg |
| Uses: | Western Blot: use at a concentration of 1 ug/ml. Immunoprecipitation: assay dependent. Not tested in other applications.Optimal dilutions / concentrations should be determined by the end user.By Western blot, this antibody detects an ~67 kDa protein repr |
| Application Summary: | IP, WB |
| General References: | General / background references:Hata Y & Sudhof TC A novel ubiquitous form of Munc-18 interacts with multiple syntaxins. Use of the yeast two-hybrid system to study interactions between proteins involved in membrane traffic. J Biol Chem 270:13022-8 (1995) |