| request information: | |
| Catalog Code: | NB120-3430 |
| Product Name: | SCAMP 1 Antibody |
| Product Description: | Rabbit Polyclonal anti-SCAMP 1 |
| Clonality: | Polyclonal |
| ListPrice: | 285 |
| Immunogen: | Synthetic Peptide: M(1)SDFDSNPFADPDLNNP(17)C. Immunizing peptide corresponds to amino acid residues 1-17 from human SCAMP 1. This sequence is completely conserved between human, rat, and porcine SCAMP 1. |
| Specificity: | NB120-3430 immunizing peptide corresponds to amino acid residues 1-17 from human SCAMP 1. This sequence is completely conserved between human, rat, and porcine SCAMP 1. |
| Cross Reactivity: | Cross-reacts with Rat and Pig.Expected to cross-react with Human due to sequence homology.Not yet tested in other species. |
| Packaging: | 0.1 mg Immunogen affinity purified Rabbit IgG. |
| Uses: | Western Blot: use at a concentration of 0.3 ug/ml.Immunoprecipitation: assay dependent. Not tested in other applications.Optimal dilution / concentration should be determined by the end user.By Western blot, this antibody detects an ~31 kDa protein representing SCAMP 1 rat brain homogenate. |
| Background: | Secretory carrier membrane proteins (SCAMPs) are proteins that are components of post-Golgi membranes. These ubiquitously expressed proteins are implicated to function in membrane trafficking. In fibroblasts, SCAMPs are concentrated in compartments that are involved in the recycling of cell surface receptors and endocytosis. In neurons, SCAMPs are associated with synaptic vesicles, secretion granules and transporter vesicles. Of the three known SCAMPs, SCAMP 1 is the most abundant. SCAMP 1 has been shown to be required for the full execution of stable exocytosis in mast cells. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | PBS |
| Application Summary: | immunoprecipitation , Western Blot 1 µg/ml |
| Species Summary: | Rt, Po |
| Alternate Names: | anti-SCAMP 1 antibody, anti-SCAMP 37 antibody,anti-SCAMP antibody , anti-SCAMP37 antibody, anti-Secretory carrier associated membrane protein 1 antibody, anti-Secretory carrier membrane protein 1 antibody, anti-Secretory carrier membrane protein antibody |
| Package Size: | 0.1 mg |
| Preservative: | 1 mg/ml BSA and 0.05% sodium azide |
| General References: | General / background references:Windoffer R et al. Tissue expression of the vesicle protein pantophysin. Cell Tissue Res 296:499-510 (1999). |
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