| Catalog Code: | NB120-3381 |
| Product Type: | Primary Antibody |
| Product Name: | MRP 6 Antibody |
| List Price: | 330 |
| Clonality: | Monoclonal |
| Gene ID: | 368 |
| Host: | Rat |
| Clone: | M6II-31 |
| Isotype: | IgG2a |
| Product Description: | Rat Monoclonal anti-MRP 6 (M6II-31) |
| Cross Reactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Species Summary: | Hu |
| Background: | The human multidrug-resistance protein (MRP) gene family is composed of multiple members including MRP 1, MRP 2 or cMOAT, and four other homologous genes, called MRP 3, MRP 4, MRP 5, and MRP 6. The substrate range of MRP 6 has not been fully determined an |
| Immunogen: | Bacterial fusion protein of human MRP 6, containing amino acids 764-964, spanning the putative 12th transmembrane region as well as predicted internal and external regions of the protein. |
| Specificity: | This antibody detects with MRP 6. This antibody does not cross-react with MDR 1,MRP 1, MRP 2 or MRP 3, MRP 4 & MRP 5. |
| Purity: | Tissue culture supernatant |
| Buffer: | Tissue culture supernatant with 0.1% sodium azide and 1% BSA |
| Packaging: | 250 microlitres Liquid. |
| Package Size: | 0.25 ml |
| Uses: | Western blotting: use at a dilution of 1/20 to 1/50.FACS: assay dependent.Immunocytochemistry: use at a dilution of 1/20 - 1/50 on acetone fixed cell preparations.Immunohistochemistry: use at a dilution of 1/20 - 1/50 on frozen and formaldehyde-fixed para |
| Application Summary: | IHC, ICC, WB |
| General References: | General references:Scheffer GL, et al., (2002) MRP6 (ABCC6) detection in normal human tissuesand tumors. Lab Invest. 2002 Apr;82(4):515-8.Bergen AA, et al., (2000) Mutations in ABCC6 cause pseudoxanthomaelasticum. Nat Genet. 2000 Jun;25(2):228-31.Scheffer |