| Catalog Code: | NB120-3309 |
| Product Type: | Primary Antibody |
| Product Name: | Synuclein Antibody |
| List Price: | 330 |
| Clonality: | Monoclonal |
| Gene ID: | 6622 |
| Host: | Mouse |
| Clone: | syn204 |
| Isotype: | IgG2a kappa |
| Product Description: | Mouse Monoclonal anti-Synuclein (syn204) |
| Cross Reactivity: | Cross-reacts with Human.Does not cross-react with Rat or Mouse.Not yet tested in other species. |
| Species Summary: | Hu, Rt(-), Mu(-) |
| Background: | Synnuclein family of proteins is abundantly expressed in neuronal cytosol and presynaptic terminals. In vertebrates they are encoded by three different genes. Synucleins have been specifically implemented in three major diseases: Alzheimer's (AD), Parkins |
| Alternate Names: | anti-Non-A beta component of AD amyloid antibody, anti-Non-A4 component of amyloid precursor antibody, anti-NACP antibody |
| Immunogen: | Recombinant full length protein (Human). |
| Specificity: | ab3309 is highly specific for alpha synucleinand does not react with beta and gamma synucleins. |
| Buffer: | 10mM PBS, pH7.4, 0.2%BSA, 0.09% sodium azide |
| Packaging: | 0.5 ml Mouse ascites. |
| Package Size: | 0.5 ml |
| Uses: | Western Blotting: use at a concentration of 1 - 2ug / ml for 2 hrs at RT.Not tested in other applications.Optimal dilutions / concentrations should be determined by the end user.By Western blot, this antibody detects a band of 14 kDa, which corresponds to |
| Application Summary: | WB |
| Storage: | Store at 4C. Do not freeze. |
| General References: | General / background references:Giasson BI et al. A panel of epitope-specific antibodies detects protein domains distributed throughout human alpha-synuclein in Lewy bodies of Parkinson's disease. J Neurosci Res 59:528-33 (2000). |