| CatalogCode: | NB120-3085 |
| ProductName: | Cyclin D2 Antibody |
| Product Description: | Mouse Monoclonal anti-Cyclin D2 (DCS-3.1) |
| Clone: | DCS-3.1 |
| Clonality: | Monoclonal |
| Immunogen: | Purified human recombinant full length cyclin D2 protein. |
| CrossReactivity: | Cross-reacts with Human, Rat and Mouse. Not yet tested in other species. |
| Packaging: | 0.5 ml protein A purified Mouse ascites. |
| Uses: | Flow cytometry / FACS: assay dependent. Functional studies: assay dependent. Immunofluorescence: assay dependent. Immunoprecipitation (with protein A): use at a concentration of 2ug/mg protein lysate (native and denatured).Western blot: assay dependent. By Western blot, this antibody detects a band of ~ 34 kDa, which corresponds to the predicted molecular weight of Cyclin D2. |
| Localization: | Nuclear. |
| Control: | U-2-OS, C82, RD, Bristol-8, or LoVo36 cells. Please note that T47D, ZR75, SKBR3, MCF-7, BT-20, MDA46 |
| Background: | Cyclin D2 is a G1 cyclin required for G1 phase progression and is a strong candidate for a proto oncogene. Cyclin D2 can phosphorylate pRB when associated with cdk 4 and / or cdk 6. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | protein A purified |
| Isotype: | IgG2a kappa |
| Host_Name: | Mouse |
| Buffer: | 10mM PBS, pH7.4, 0.2%BSA |
| ListPrice: | 325 |
| AppSummary: | FACS, IF, IP, WB, FC |
| SpeciesSummary: | Hu, Mu, Rt |
| ALTnames: | Anti-CCND 2 antibody; Anti-CCND2 antibody; Anti-CyclinD2 antibody; Anti-G1/S specific cyclin D2 antibody; Anti-KIAK0002 antibody; Anti-MGC102758 antibody |
| ProteinTarget: | Cyclin D2 |
| PackageSize: | 0.5 ml |
| GeneralRef: | This product has been used in:Lukas J et al. Cyclin D2 is a moderately oscillating nucleoprotein required for G1 phase progression in specific cell types. Oncogene 10:2125-34 (1995). General / background references:Bartkova J et al. Abnormal patterns of D-type cyclin expression and G1 regulation in human head and neck cancer. Cancer Res 55:949-56 (1995). |
| NotesMain: | This antibody has replaced ab6279, and is the same as ab3085. |
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