| Catalog Code: | NB120-2958 |
| Product Type: | Primary Antibody |
| Product Name: | Nck Antibody |
| List Price: | 330 |
| Clonality: | Polyclonal |
| Gene ID: | 4690 |
| Host: | Rabbit |
| Isotype: | IgG |
| Product Description: | Rabbit Polyclonal anti-Nck |
| Cross Reactivity: | Cross-reacts with Human, Rat and Mouse.Not yet tested in other species. |
| Species Summary: | Hu, Rt, Mu |
| Background: | Nck is a highly conserved protein that has one SH2 and three SH3 domains. It is ubiquitously expressed in mammalian tissues. Nck is phosphorylated on tyrosine, serine, and threonine residues in response to stimulation by EGF and PDGF. Nck has been propose |
| Immunogen: | Recombinant full length protein (Human). |
| Localization: | Cytoplasmic |
| Purity: | Protein A purified |
| Buffer: | 10mM PBS, pH7.4, 0.2%BSA, 0.09% sodium azide |
| Packaging: | 500 microlitres Liquid. |
| Package Size: | 0.5 ml |
| Uses: | Immunofluorescence: assay dependent.Immunoprecipitation (with protein A, denatured): use at a concentration of 10ug / mg of lysate.Western Blotting: use at a concentration of 5 - 10ug / ml for 2hrs at RT.Not tested in other applications.Optimal dilutions |
| Application Summary: | IF, IP, WB |
| General References: | General / background references:Kitamura Y et al. Interaction of Nck-associated protein 1 with activated GTP-binding protein Rac. Biochem J 322 (Pt 3):873-8 (1997). Lawe DC et al. The Nck SH2/SH3 adaptor protein is present in the nucleus a |
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