| Catalog Code: | NB120-2869 |
| Product Type: | Primary Antibody |
| Product Name: | Sodium / Calcium Exchanger Antibody |
| List Price: | 295 |
| Clonality: | Monoclonal |
| Gene ID: | 57419 |
| Host: | Mouse |
| Clone: | C2C12 |
| Isotype: | IgM |
| Product Description: | Mouse Monoclonal anti-Sodium / Calcium Exchanger (C2C12) |
| Cross Reactivity: | Cross-reacts with Human, Rabbit, Rat, Dog and Guinea pig. Not yet tested in other species. |
| Species Summary: | Ca, Hu, Rt, Rb, Gp |
| Background: | The sodium/calcium exchanger of cardiac sarcolemma rapidly transports calcium during excitation-contraction coupling and is the dominant myocardial calcium efflux mechanism. The sodium/calcium exchanger uses the transmembrane sodium gradient to catalyze c |
| Immunogen: | Purified canine cardiac sodium / calcium exchanger. |
| Epitope: | This antibody recognizes an epitope between amino acids 371-525 on the intracellular side of the plasma membrane. |
| Purity: | Ascites |
| Buffer: | PBS |
| Packaging: | 0.1 ml Ascites Mouse ascites. |
| Package Size: | 0.1 ml |
| Uses: | Immunofluorescence: use at a dilution of 1/200. Western Blot: use at a dilution of 1/1000. Immunoprecipitation: Assay dependent. By Western blot, this antibody detects a 120 kDa protein representing the sodium / calcium exchanger from guinea pig cardiac e |
| Application Summary: | IF, IP, WB |
| General References: | This product has been used in:Frank JS et al. Distribution of the Na(+)-Ca2+ exchange protein in mammalian cardiac myocytes: an immunofluorescence and immunocolloidal gold-labeling study. J Cell Biol 117:337-45 (1992). General / background |