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| Catalog Code: | NB120-2524 |
| Product Name: | Blood Group B antigen Antibody |
| Product Description: | Mouse Monoclonal anti-Blood Group B antigen (HEB-29) |
| Clone: | HEB-29 |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Immunogen: | Mixture of erythrocytes of blood group B and glycoprotein fraction isolated from the saliva of secretors with blood group B. |
| Specificity: | This antibody recognizes human blood group B antigens. The specifity of the antibody HEB-29 was confirmed by comparison of specifity and reactivity to standard reagent using >5.000 samples of blood. |
| Cross Reactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | 1 ml Tissue culture supernatant Mouse ascites. |
| Uses: | In agglutination tests, the minimum titre is 1:128 with erythrocytes of blood group B. |
| Background: | Blood group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Tissue culture supernatant |
| Isotype: | IgM |
| Host Name: | Mouse |
| Buffer: | Tissue Culture Supernatant |
| Application Summary: | immunohistochemistry (P): Use at an assay dependent dilution, Aggregation |
| Species Summary: | Hu |
| Package Size: | 1 ml |
| General References: | This product has been used in:Vanak J et al. Detection of blood group A antigen expression in human colon cancer using monoclonal antibodies with different specificities. Neoplasma 36:479-88 (1989). |
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