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| Catalog Code: | NB120-2405 |
| Product Name: | Macroglobulin alpha 2 Antibody |
| Product Description: | Rabbit Polyclonal anti-Macroglobulin alpha 2 |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Immunogen: | Purified alpha-2-macroglobulin. |
| Specificity: | The antibody is specific against human alpha-2-allmacroglobulin. |
| Cross Reactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | 0.5 ml Whole Rabbit antisera. |
| Uses: | This antibody may be diluted to a titer of 1:50-1:100 in an ABC allmethod. We suggest an incubation period of 30 minutes at room temperature. Suitable for formalin/paraffin tissues. |
| Localization: | Cytoplasmic |
| Background: | Alpha 2 macroglobulin is a serum protein which is mainly synthesised in the liver. It functions as a broad range irreversible proteinase inhibitor that forms a "trap" around most proteases. Alpha 2 macroglobulin is a tetrameric molecule, and with a molecular weight of 720 kDa, it so large a molecule that it tends to remain intravascular. Following conformational change the proteinase is deposited within a central cavity where it is still active but prevented from further contact with its substrate. Removal of the complex is mediated by the generation of recognition sites which react with receptors on a variety of cells including macrophages and liver cells. Alpha 2 macroglobulin is localized on the surface of peripheral blood lymphocytes. |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | Whole antisera |
| Isotype: | unknown |
| Host Name: | Rabbit |
| Buffer: | Constituents: Antiserum |
| Application Summary: | immunohistochemistry-Fr, immunohistochemistry-P |
| Species Summary: | Hu, |
| Alternate Names: | anti-A2M antibody, anti-Alpha 2 M antibody, anti-CPAMD5 antibody, anti-FWP007 antibody, anti-S863 7 antibody |
| Package Size: | 0.5 ml |
| Preservative: | Sodium Azide |
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more information: | company product webpage |