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| Catalog Code: | NB120-2168 |
| Product Name: | PARP Antibody |
| Product Description: | Rabbit Polyclonal anti-PARP |
| Clonality: | Polyclonal |
| ListPrice: | 315 |
| Immunogen: | A synthetic peptide from the N-terminal region of human PARP. |
| Specificity: | This antibody reacts with a 116 kDa protein, known as PARP (Poly ADP Ribose Polymerase). |
| Cross Reactivity: | Cross-reacts with Human, Rat and Mouse. Not yet tested in other species. |
| Packaging: | 0.5 ml Rabbit antisera. |
| Uses: | IHC: This antibody may be diluted to a titer of 1:25-1:50 in an ABC method. We suggest an incubation period of 30 minutes at room temperature. However, depending upon the fixation conditions and the staining system employed, optimal incubation conditions and antibody dilutions should be determined by the user. High temperature treatment of formalin-fixed tissue sections with 10mM citrate buffer, pH 6.0 must be performed prior to the immunostaining. |
| Localization: | Nuclear |
| Storage: | Store at 4C. Do not freeze. |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | PBS |
| Application Summary: | immunohistochemistry 1:25-1:50, Western Blot |
| Species Summary: | Hu, Mu, Rt, |
| Alternate Names: | anti-ADP ribosyltransferase NAD+ antibody, anti-pADPRT1 antibody, anti-PARP1 antibody, anti-Poly adenosine diphosphate ADP ribose polymerase antibody, anti-Poly ADP ribose polymerase 1 antibody, anti-Poly ADP ribose synthetase 1 antibody, anti-PPOL antibody |
| Package Size: | 0.5 ml |
| Preservative: | Sodium azide |
| General References: | Tewari M <i>et al.</i> Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. <i>Cell</i> <b>81</b>:801-9 (1995). <PUBMED:7774019>Lamarre D <i>et al.</i> Structural and functional analysis of poly(ADP ribose) polymerase: an immunological study. <i>Biochim Biophys Acta</i> <b>950</b>:147-60 (1988). <PUBMED:2454668> |
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