| CatalogCode: | NB120-19884 |
| ProductName: | Bcl10 Antibody |
| Product Description: | Rabbit Polyclonal anti-Bcl10 |
| Clonality: | Polyclonal |
| Immunogen: | Synthetic peptide (Human) (N terminal). |
| CrossReactivity: | Cross-reacts with Human, Mouse and Rat.Not yet tested in other species. |
| Packaging: | 0.25 mg |
| Uses: | WB: Use Ab 5ug/ml for 2hrs at RT. Predicted molecular weight: 31 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Cytoplasmic. Appears to have a perinuclear, compact and filamentous pattern of expression. Also found in the nucleus of several types of tumor cells. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Isotype: | IgG |
| Host_Name: | Rabbit |
| Buffer: | Preservative: Sodium AzideConstituents: BSA, 10mM PBS. pH 7.4 |
| ListPrice: | 330 |
| NovusRef: | 1. Bhattacharyya, S., R. Gill, et al. (2008). Toll-like receptor 4 mediates induction of Bcl10-NFkappa B-IL-8 inflammatory pathway by Carrageenan in human intestinal epithelial cells. J. Biol. Chem.: M708833200. |
| AppSummary: | WB |
| ProteinTarget: | Bcl10 |
| PackageSize: | 0.25 mg |
| GeneralRef: | Willis TG et al. Bcl10 is involved in t(1;14)(p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types. Cell 96:35-45 (1999). PUBMED:9989495 Yan M et al. mE10, a novel caspase recruitment domain-containing proapoptotic molecule. J Biol Chem> 274:10287-92 (1999). PUBMED:10187815 Thome M et al. Equine herpesvirus-2 E10 gene product, but not its cellular homologue, activates NF-kappaB transcription factor and c-Jun N-terminal kinase. J Biol Chem 274:9962-8 (1999). PUBMED:10187771 Zhang Q et al. Inactivating mutations and overexpression of BCL10, a caspase recruitment domain-containing gene, in MALT lymphoma with t(1;14)(p22;q32). Nat Genet 22:63-8 (1999). PUBMED:10319863 Koseki T et al. CIPER, a novel NF kappaB-activating protein containing a caspase recruitment domain with homology to Herpesvirus-2 protein E10. J Biol Chem 274:9955-61 (1999). PUBMED:10187770 Srinivasula SM et al. CLAP, a novel caspase recruitment domain-containing protein in the tumor necrosis factor receptor pathway, regulates NF-kappaB activation and apoptosis. J Biol Chem 274:17946-54 (1999). PUBMED:10364242 |