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| Catalog Code: | NB120-19349 |
| Product Name: | Estrogen Receptor alpha Antibody |
| Product Description: | Mouse Monoclonal anti-Estrogen Receptor alpha (EVG F9) |
| Clone: | EVG F9 |
| Clonality: | Monoclonal |
| ListPrice: | 285 |
| Immunogen: | Synthetic peptide: TVREAGPPAFYRPNS, corresponding to amino acids 140-154 of Human Estrogen Receptor alpha. Synthetic peptide: EVGMMKGGIRKDRRGGR, corresponding to amino acids 247-263 of Human Estrogen Receptor alpha. |
| Specificity: | Detects estrogen receptor alpha in human and rabbit samples. |
| Cross Reactivity: | Cross-reacts with Human and Rabbit.Not yet tested in other species. |
| Packaging: | 0.1 ml Mouse ascites. |
| Uses: | IHC-P: 1/200. IP: Use at an assay dependent dilution. WB: 1/1000. Detects a band of approximately 68 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Nuclear |
| Background: | Estrogen Receptor alpha is a 65 kDa protein and a member of the steroid family of nuclear receptors. Estrogen Receptor alpha is a ligand-activated transcription factor that, when bound to estrogen, induces a conformational change that allows dimerization and binding to estrogen response element sequences. When bound to DNA, Estrogen Receptor alpha can positively or negatively regulate gene transcription. Like other steroid hormone receptors, Estrogen Receptors are intracellular proteins. Estrogen Receptors play an important role in regulating mammary gland growth and differentiation. Breast tumors that are ER positive may also show a more favorable response to anti-estrogen therapies |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Ascites |
| Isotype: | IgM |
| Host Name: | Mouse |
| Application Summary: | Immunohistochemistry-Paraffin, immunoprecipitation, Western Blot, |
| Species Summary: | Hu, Rb, |
| Alternate Names: | anti-DKFZp686N23123 antibody, anti-ER alpha antibody, anti-ER antibody, anti-Era antibody, anti-ESR 1 antibody, anti-ESR antibody, anti-ESR1 antibody, anti-ESRA antibody, anti-Estradiol receptor antibody, anti-Estrogen receptor 1 antibody, anti-Estrogen receptor antibody, anti-Major ORF antibody, anti-NR3A1 antibody |
| Package Size: | 0.1 ml |
| Preservative: | 0.05% sodium azide. |
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more information: | company product webpage |