| CatalogCode: | NB120-18376 |
| ProductName: | PARP Antibody |
| Product Description: | Mouse Monoclonal anti-PARP (5A5) |
| Clone: | 5A5 |
| Clonality: | Monoclonal |
| Immunogen: | Recombinant fragment (Human). |
| CrossReactivity: | Cross-reacts with Human and Mouse. Not yet tested in other species. |
| Packaging: | 0.1 mg protein G purified Mouse ascites. |
| Uses: | IF: Use at an assay dependent dilution. WB: Use at a concentration of 1 ug/ml. Detects a band of approximately 113 kDa. |
| Localization: | Nuclear |
| Storage: | Store at 4C. Do not freeze. |
| Purity: | protein G purified |
| Isotype: | IgG1 kappa |
| Host_Name: | Mouse |
| Buffer: | Constituents: PBS. pH 7.2 |
| ListPrice: | 295 |
| AppSummary: | IF, WB |
| SpeciesSummary: | Hu, Mu |
| ProteinTarget: | PARP |
| PackageSize: | 0.1 mg |
| GeneralRef: | General / background references:Noël G et al. Poly(ADP-ribose) polymerase (PARP-1) is not involved in DNA double-strand break recovery. BMC Cell Biol 4:7 (2003). Ying W et al. Poly(ADP-ribose) glycohydrolase mediates oxidative and excitotoxic neuronal death. Proc Natl Acad Sci U S A 98:12227-32 (2001). Ikejima M et al. The zinc fingers of human poly(ADP-ribose) polymerase are differentially required for the recognition of DNA breaks and nicks and the consequent enzyme activation. Other structures recognize intact DNA. J Biol Chem 265:21907-13 (1990). Cherney BW et al. cDNA sequence, protein structure, and chromosomal location of the human gene for poly(ADP-ribose) polymerase. Proc Natl Acad Sci U S A 84:8370-4 (1987). |
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