| request information: |
|
| Catalog Code: | NB120-18321 |
| Product Name: | Cdc25A Phosphospecific Antibody |
| Product Description: | Rabbit Polyclonal anti-Cdc25A [Ser17] |
| Clonality: | Polyclonal |
| ListPrice: | 325 |
| Immunogen: | Synthetic peptide (Human). |
| Cross Reactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | WB: 1/500. Detects a band of approximately 59 kDa (predicted molecular weight: 59 kDa). |
| Localization: | Nuclear membrane |
| Background: | Cyclin dependent kinases are positively regulated by association with cyclins and negatively regulated by binding to inhibitory subunits. The activity of cyclin dependent kinases is also regulated by the phosphorylation status, which is controlled by the antagonistic action of Wee1 kinase and CDC25 phosphatases. Three CDC25 genes are present in human cells: CDC25A, CDC25B, and CDC25C. These three genes function at different phases of the cell cycle. Whereas CDC25A and CDC25B are expressed throughout the cell cycle, with peak expression in G1 for CDC25A and in both G1 S phase and G2 for CDC25B, CDC25C is predominantly expressed in G2. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | Constituents: 50% Glycerol, PBS. pH 7.2 |
| Application Summary: | Western Blot |
| Species Summary: | Hu, |
| Alternate Names: | anti-Cdc 25a antibody, anti-CDC25A2 antibody, anti-Cell division cycle 25A antibody, anti-Cell division cycle 25A isoform a antibody, anti-Cell division cycle 25A isoform b antibody, anti-Dual specificity phosphatase CDC25A antibody, anti-M phase inducer phosphatase 1 antibody |
| Package Size: | 0.1 ml |
| Preservative: | 0.09% Sodium Azide |
| Phosphorylated: | Ser17 |
order or
more information: | company product webpage |