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| Catalog Code: | NB120-18305 |
| Product Name: | REA Antibody |
| Product Description: | Rabbit Polyclonal anti-REA |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Immunogen: | Partial recombinant BAP37 protein at the C-terminus. |
| Specificity: | Reacts with the estrogen receptor, prohibitin, and IgM. |
| Cross Reactivity: | Cross-reacts with Human and Mouse. Not yet tested in other species. |
| Packaging: | 0.1 ml Immunogen affinity purified Rabbit antisera. |
| Uses: | It is recommended that the reagent be titrated for optimal performance for each application. |
| Localization: | Mitochondrial |
| Background: | BAP37, (also known as B-cell receptor-associated protein, repressor of estrogen receptor activity, and prohibitin 2) is a 37 kD erythrocyte band 7 integral membrane protein that contains an SPFH domain. BAP37 is located in the inner mitochondrial membrane that selectively potentiates the inhibitory effectiveness of antiestrogen-occupied ER. BAP37 plays a possible role in cell aging and acts as a mitochondrial protein chaperone. This protein has been shown to interact with the estrogen receptor, prohibitin, and IgM. |
| Storage: | Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles. |
| Purity: | Immunogen affinity purified |
| Isotype: | IgG |
| Host Name: | Rabbit |
| Buffer: | PBS, pH 7.2, 50% Glycerol |
| Application Summary: | Western Blot 10ul/5ml antibody (Mini-gel) |
| Species Summary: | Hu, Mu |
| Alternate Names: | anti-REA antibody, anti-Repressor of Estrogen Activity antibody, anti-PHB2 antibody, anti-PHB-2 antibody, anti-Prohibitin 2 antibody, anti-BAP antibody, anti-BAP37 antibody, anti-BCAP37 antibody, anti-B-Cell Associated Protein 37 kDa antibody, anti-PNAS141 antibody, anti-PNAS-141 antibody, anti-p22 antibody |
| Package Size: | 0.1 ml |
| Preservative: | 0.09% Sodium Azide |
| General References: | 1. Terashima, M., et al., 1994. EMBO J. 13:3782. 2. Montano, M., et al., 1999. PNAS 96:6947 3. Nijtmans, L., et al., 2000. EMBO J. 19:2444. 4. Piper, P., et al., 2002. Aging Cell 1:149. |
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