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| Catalog Code: | NB120-17893 |
| Product Name: | Fibrinogen Antibody |
| Product Description: | Chicken Polyclonal anti-Fibrinogen |
| Clonality: | Polyclonal |
| ListPrice: | 295 |
| Concentration: | 1 mg/ml |
| Immunogen: | Synthetic peptide (Human fibrinogen mixed peptides). |
| Cross Reactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Packaging: | 0.05 mg IgG purified Chicken IgY |
| Uses: | ELISA: 1/1000 - 1/5000. WB: 1/1000 - 1/5000. Predicted molecular weight: 95 kDa. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Secreted |
| Background: | Fibrinogen is the main protein of blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases. The normal fibrinogen concentration in plasma is about 3 mg/ml. The elevated level of fibrinogen in patient's blood is regarded as an independent risk factor for cardiovascular diseases. An increase in blood fibrinogen concentration was shown to be a strong predictor of coronary heart disease (Sonel A. et al, and Rapold H.J. et al). All these facts make fibrinogen an important parameter in the diagnosis of cardiovascular diseases. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | IgG purified |
| Isotype: | IgY |
| Host Name: | Chicken |
| Buffer: | Phosphate-Buffered Saline. |
| Application Summary: | ELISA, Western Blot |
| Species Summary: | Hu, |
| Alternate Names: | anti-FGA antibody, anti-FGA protein antibody, anti-FGB antibody, anti-FGG antibody, anti-Fib2 antibody, anti-Fibrinogen A alpha polypeptide chain antibody, anti-Fibrinogen alpha chain antibody, anti-Fibrinogen beta chain antibody, anti-Fibrinogen gamma chain antibody, anti-MGC104327 antibody, anti-MGC119422 antibody, anti-MGC119423 antibody, anti-MGC119425 antibody, anti-MGC120405 antibody |
| Package Size: | 0.5 mg |
| Preservative: | 0.01% Sodium Azide |
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