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| Catalog Code: | NB120-17853 |
| Product Name: | Actin Antibody |
| Product Description: | Mouse Monoclonal anti-Actin (SPM160) |
| Clone: | SPM160 |
| Clonality: | Monoclonal |
| ListPrice: | 285 |
| Concentration: | 1 mg/ml |
| Immunogen: | Purified actin |
| Specificity: | This antibody reacts with alpha-smooth muscle as well as alpha-skeletal and alpha-cardiac (sarcomeric) isoform of actin. It is a pan muscle actin and reacts with tumors arising from smooth muscle (leiomyosarcomas) as well as skeletal muscle (rhabdomyosarcomas). |
| Cross Reactivity: | Cross-reacts with Human, Mouse, Rat, Cow, Dog, Horse and Pig.Not yet tested in other species. |
| Packaging: | 7 ml protein G purified Mouse IgG. |
| Uses: | IF: Use at an assay dependent dilution. IHC-P: Ready to use for 30 min at RT. No special pretreatment is required for histochemical staining of formalin/paraffin tissues. Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Cytoplasmic |
| Background: | The two major cytoskeletal proteins implicated in cell motility are actin and myosin. Actin and myosin are constituents of many cell types and are involved in a myriad of cellular processes including locomotion, secretion, cytoplasmic streaming, phagocytosis and cytokinesis. Although actin is one of the most conserved eukaryotic proteins, it is expressed in mammals and birds as at least six isoforms characterized by electrophoresis and amino acid sequence analysis. Four of them represent the differentiation markers of muscle tissues and two are found in practically all cells. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | protein G purified |
| Isotype: | IgG1 kappa |
| Host Name: | Mouse |
| Buffer: | 10mM PBS, pH 7.4 with BSA |
| Application Summary: | immunofluorescence, immunohistochemistry-P |
| Species Summary: | Bv, Ca, Hu, Mu, Po, Rt, Eq, |
| Alternate Names: | anti-ActG antibody, anti-ActG1 antibody, anti-Actin antibody, anti-Gamma1 antibody, anti-DFNA20 antibody |
| Package Size: | 7 ml |
| Preservative: | Sodium Azide |
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more information: | company product webpage |