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| Catalog Code: | NB120-17765 |
| Product Name: | Cytokeratin 15 Antibody |
| Product Description: | Mouse Monoclonal anti-Cytokeratin 15 (SPM190) |
| Clone: | SPM190 |
| Clonality: | Monoclonal |
| ListPrice: | 325 |
| Immunogen: | Synthetic peptide: MTTTFLQTSS STFGGGS, corresponding to C terminal amino acids 17 of Human Cytokeratin 15. |
| Cross Reactivity: | Cross-reacts with Human, Mouse, Rat and Cow.Not yet tested in other species. |
| Packaging: | 7 ml Mouse ascites. |
| Uses: | IHC-P: Ready-to-use for 30 min at RT. Perform heat mediated antigen retrieval before commencing with IHC staining protocol - boil tissue sections in 10mM citrate buffer, pH 6.0 for 10 min followed by cooling at RT for 20 min. |
| Localization: | Cytoplasmic |
| Background: | Keratin 15 is a type I keratin without a defined type II partner. Keratin 15 is expressed primarily in the basal keratinocytes of stratified tissues, including the fetal epidermis and fetal nail. Expression of keratin 15 is downregulated in some hyperproliferating situations, such as psoriasis and hypertrophic scars. Because keratinocytes in psoriasis and hypertrophic scars are activated, it is suggested that keratin 15 expression is not compatible with keratinocyte activation and the keratin 15 gene is downregulated to maintain the activated phenotype. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Isotype: | IgG2a kappa |
| Host Name: | Mouse |
| Buffer: | 50mM Tris buffer with 1%BSA |
| Application Summary: | Immunohistochemistry-Paraffin |
| Species Summary: | Bv, Hu, Mu, Rt, |
| Alternate Names: | Anti-CK 15 antibody, Anti-CK15 antibody, Anti-Cytokeratin15 antibody, Anti-K15 antibody, Anti-K1CO antibody, Anti-Keratin 15 antibody, Anti-Keratin 15 basic antibody, Anti-Keratin 15 beta antibody, Anti-Keratin complex 1 acidic gene 15 antibody, Anti-Keratin type I cytoskeletal 15 Anti-antibody, Anti-Keratin15 antibody, Anti-KRT 15 antibody, Anti-KRT15 antibody, Anti-KRTB antibody, Anti-KRTL15 antibody, Anti-Type I cytoskeletal 15 antibody |
| Package Size: | 7 ml |
| Preservative: | 0.1% sodium azide |
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more information: | company product webpage |
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