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| Catalog Code: | NB120-17249 |
| Product Name: | Bcl6 Antibody |
| Product Description: | Mouse Monoclonal anti-Bcl6 (PG-B6P) |
| Clone: | PG-B6P |
| Clonality: | Monoclonal |
| ListPrice: | 295 |
| Concentration: | 1 mg/ml |
| Immunogen: | Prokaryotic recombinant protein corresponding to amino acids 3-484 of the human Bcl6 protein. |
| Cross Reactivity: | Cross-reacts with Human. Not yet tested in other species. |
| Packaging: | 0.5 ml Tissue culture supernatant Mouse ascites. |
| Uses: | IHC-P: Use with the ABC method. High temperature antigen unmasking using 1mM EDTA (pH 8.0) is recommended for formalin fixed paraffin tissues sections. |
| Localization: | Nuclear |
| Background: | This antibody reacts with Bcl6 gene product in follicular lymphomas, diffuse large B cell lymphomas, Burkitt's lymphomas and in nodular, lymphocyte predominant Hodgkin's disease. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | Tissue culture supernatant |
| Isotype: | IgG1 kappa |
| Host Name: | Mouse |
| Buffer: | Tissue culture supernatant |
| Application Summary: | immunohistochemistry P, 1/10 - 1/25, |
| Species Summary: | Hu, |
| Package Size: | 0.5 ml |
| Preservative: | Sodium Azide |
| General References: | General / background references:Flenghi L et al. Monoclonal antibodies PG-B6a and PG-B6p recognize, respectively, a highly conserved and a formol-resistant epitope on the human BCL-6 protein amino-terminal region. Am J Pathol 148:1543-55 (1996). Otsuki T et al. Analysis of LAZ3 (BCL-6) status in B-cell non-Hodgkin's lymphomas: results of rearrangement and gene expression studies and a mutational analysis of coding region sequences. Blood 85:2877-84 (1995). Pescarmona E et al. Analysis of the BCL-6 gene configuration in diffuse B-cell non-Hodgkin's lymphomas and Hodgkin's disease. J Pathol 177:21-5 (1995). |
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more information: | company product webpage |