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| Catalog Code: | NB120-17083 |
| Product Name: | CD99 Ewing Sarcoma Antibody |
| Product Description: | Mouse Monoclonal anti-CD99 Ewing Sarcoma (HO36-1.1) |
| Clone: | HO36-1.1 |
| Clonality: | Monoclonal |
| ListPrice: | 285 |
| Immunogen: | Tissue / cell preparation (purified E-rosette forming cells from human peripheral blood lymphocytes). |
| Specificity: | This antibody is specific to a sialoglycoprotein of 27-32 kD known as CD99 or MIC2 gene product. CD99 is expressed on the cell membrane of some lymphocytes, cortical thymocytes and granulosa cells of the ovary, sertoli cells of testis, pancreatic islet cells and some endothelial cells. Mature granulocytes express very little or no CD99. |
| Cross Reactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Packaging: | 0.5 ml IgM purified Mouse IgM. |
| Uses: | IHC-P: 1/25 - 1/75. Formalin-fixed paraffin-embedded tissue sections require high temperature antigen unmasking with 10 mM citrate buffer, pH 6.0 prior to immunostaining.Not tested in other applications.Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Cell Membrane |
| Background: | CD99 is a 32kDa glycoprotein, which is thought to be involved in cell adhesion processes. Expression of CD99 is a characteristic of cells from Ewing's sarcoma and primitive peripheral neuroectodermal tumours. However expression is also seen in certain normal cells such as pancreatic islet cells, cortical thymocytes, Sertoli cells and ovarian granulosa cells. Mature granulocytes express very little or no CD99. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | IgM purified |
| Isotype: | IgM |
| Host Name: | Mouse |
| Application Summary: | immunohistochemistry-P |
| Species Summary: | Hu, |
| Alternate Names: | anti-12E7 antibody, anti-Antigen identified by monoclonal 12E7 Y homolog antibody, anti-Antigen identified by monoclonal antibodies 12E7 F21 and O13 antibody, anti-CD 99 antibody, anti-CD99 antibody, anti-CD99 antigen antibody, anti-CD99 molecule antibody, anti-CD99X antibody, anti-E2 antigen antibody, anti-Ewing Sarcoma antibody, anti-MIC 2 antibody, anti-MIC 2X antibody, anti-MIC 2Y antibody, anti-MIC2 (monoclonal antibody 12E7) antibody, anti-MIC2 antibody, anti-MIC2X antibody, anti-MIC2Y antibody, anti-Monoclonal antibody 12E7 antibody, anti-MSK5X antibody, anti-Protein MIC2 antibody, anti-Surface antigen MIC2 antibody, anti-T cell surface glycoprotein E2 antibody, anti-T cell surface glycoprotein E2 precursor antibody, anti-T-cell surface glycoprotein E2 precursor antibody |
| Package Size: | 0.5 ml |
| Preservative: | Sodium Azide |
| General References: | General / background references:Sandrin MS et al. Expression cloning of cDNA clones encoding the human cell surface proteins HuLy-m6 and FMC29. Immunogenetics 35:283-5 (1992). |
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