| CatalogCode: | NB120-17079 |
| ProductName: | CD6 Antibody |
| Product Description: | Mouse Monoclonal anti-CD6 (SPV-L14) |
| Clone: | SPV-L14 |
| Clonality: | Monoclonal |
| Immunogen: | BALB/C mice were injected with CD8 cytotoxic T cell clone. |
| Epitope: | Not determined |
| CrossReactivity: | Cross-reacts with Human.Not yet tested in other species. |
| Packaging: | 1 ml protein A purified Mouse ascites. |
| Uses: | IHC-F: An incubation period of 30 minutes at room temperature is suggested. This antibody is not suitable for fixed paraffin sections. Optimal dilutions/concentrations should be determined by the end user. |
| Localization: | Type I membrane protein. |
| Control: | Tonsil |
| Background: | CD6 is homologous to CD5 and macrophage scavenger receptor. It is expressed on the surface of mature thymocytes, peripheral T cells, and a subset of B cells. CD6 may be involved in T-cell activation as MAb's to CD6 augment T-cell receptor (TCR)-mediated activation of T cells, and the CD6 molecule is tyrosine phosphorylated during TCR-mediated T-cell triggering. |
| Storage: | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze thaw cycles. |
| Purity: | protein A purified |
| Isotype: | IgG1 |
| Host_Name: | Mouse |
| Buffer: | PBS with 0.2% BSA |
| ListPrice: | 325 |
| AppSummary: | IHC-Fr |
| SpeciesSummary: | Hu |
| ALTnames: | anti-TP120 antibody |
| ProteinTarget: | CD6 |
| PackageSize: | 1 ml |
| GeneralRef: | General / background references:Yssel H et al. Distribution and functional analysis of a 120- to 130-kDa T-cell surface antigen. Cell Immunol 105:161-73 (1987). |